Considered the oldest pharmacy in the world, Officina Profumo-Farmaceutica di Santa Maria Novella was founded in 1221 as a Dominican friars convent when the friars were granted the use of Santa Maria Inter Vineas ("Holy Mary Among the Vines") — a small church just outside the city walls where they cultivated a botanical garden of herbs and plants to craft medicines, ointments and balms. The 'Melograno' fragrance is a bouquet of sweet floral oriental notes. It opens with fresh spicy and citrus notes, with a base of patchouli, labdanum, and musk blended with deep notes of oakmoss.